(2) • Dermal or ocular contact with solutions of ethylene oxide has caused irritation of the skin and eyes in humans. What are fire hazards and extinguishing media for ethylene oxide? Soc. Oxirane 1.2. Explosions occur , although infrequently, from the combination of ethylene oxide and alcohols or mercaptans, [Chem. TWENTY. Provides references that aid in preventing and controlling exposures to ethylene oxide. IDENTIFICATION OF THE SUBSTANCE OR MIXTURE AND OF THE SUPPLIER 1.1. Ethylene Oxide may damage the testes (male reproductive glands). The first study to establish a potential link between ethylene oxide and cancer was published in 1948, and in it, researchers found that ethylene oxide is a mutagen. Emergency Life-Support Procedures: Acute exposure to ethylene oxide may require decontamination and life support for the victims. SWIMMING POOL..1. Ethylene oxide was first discovered more than 160 years ago and signs of health risks from exposure to the gas date back 70 years. Provides a summary source of information of all potential and most … View 301 Chapter 6 MSDS EtOKit.ppt from CHEMICAL 434 at Universiti Teknologi Mara. The Ethylene Oxide Awareness for General Industry safety course from ClickSafety offers introductory-level knowledge regarding this hazardous chemical and all applicable OSHA standards. Hazards identification Prevention :Obtain special instructions before use. Ethylene oxide is not an acute health hazard but can be harmful if continually ingested over time. At 70ºF (21ºC) a nitrogen pressure of 32.6 psig (225 kPa) is required. Ethylene Oxide may damage the developing fetus. Because it is a strained ring, ethylene oxide easily participates in a number of addition reactions that result in ring-opening. SWIMMING POOLS. Congress classified it as a “hazardous air pollutant,” according to the United States Environmental Protection Agency. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. Ethylene oxide is industrially produce… Wear protective gloves. Most ethylene oxide is used up in the factories where it is produced. Ethylene Oxide Health and fire hazards of ethylene oxide How you can be exposed to ethylene oxide How we control Citing the Environmental Protection Agency (EPA) and the Centers for Disease Control and Prevention (CDC), the Washington Department of Labor & Industries cautions health care employers and others who sterilize respirators for reuse that ethylene oxide is a carcinogen that “has been linked to neurologic dysfunction and may cause other harmful effects” to the eyes, […] Safety data sheet Ethylene Oxide Creation date : 28.01.2005 Version : 2.0 DE / E SDS No. UN 1040 Ethylene Oxide UN 1040 Ethylene Oxide Labels 2.3, 2.1 Hazard number 263 Packing Instruction P200 IMDG Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Packing Instruction P200 EmS FD,SU IATA Class 2.3 UN number and proper shipping name UN 1040 Ethylene Oxide Labels 2.3, 2.1 Application of age-dependent adjustment factors (ADAFs) to the inhalation unit risk is recommended in combination with appropriate exposure data … Provides links and references to additional resources related to exposures to ethylene oxide. SWIMMING POOLS. Ethylene oxide may severely irritate or burn mucous membranes and moist skin. Notice to Interested Parties Proposition 65 Listed Chemicals Affected by Hazard Communications Standard Amendments; Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead Signal word Danger. * Ethylene is a HIGHLY FLAMMABLE and REACTIVE chemical and a DANGEROUS FIRE and EXPLOSION HAZARD. CAS number: 75–21–8 NIOSH REL: <0.1 ppm (<0.18 mg/m 3) TWA, 5 ppm (9 mg/m 3) CEILING, 10-minutes/day; NIOSH considers ethylene oxide to be a potential occupational carcinogen as defined by the OSHA carcinogen policy [29 CFR 1990]. Ethylene oxide (also known as ETO or oxirane) is a flammable gas with a somewhat sweet odor. It has been determined to be carcinogenic to humans. Ethylene Oxide Section 2. It dissolves easily in water.Ethylene oxide is a man-made chemical that is used primarily to make ethylene glycol (a chemical used to make antifreeze and polyester). TWENTY. Ethylene oxide, called oxirane by IUPAC, is an organic compound with the formula C 2H 4O. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Maximize Your Spirometry Screening and Surveillance Resources, Protect Yourself - Spirometry Breathing Test, OSHA's Small Business Guide for Ethylene Oxide, Severe Storm and Flood Recovery Assistance. OLYMPIC SIZE. Since ethylene oxide hydrolyzes to ethylene glycol which is readily biodegraded, the importance of biodegradation of ethylene oxide in the environment is … Participants can expect to focus on the properties, primary use of Ethylene Oxide, routes of … What are fire hazards and extinguishing media for ethylene oxide? ETHYLENE OXIDE IN THE HUMAN BODY. OLYMPIC SIZE. SWIMMING POOL..1. Ethylene Oxide Other means of identification. Symbol GHS02,GHS04,GHS05,GHS06,GHS08. • Acute inhalation exposure of workers to high levels of ethylene oxide has resulted in nausea, vomiting, neurological disorders, bronchitis, pulmonary edema, and emphysema. Ethylene oxide decomposes or polymer… * Exposure to Ethylene can cause headache, dizziness, fatigue, lightheadedness, confusion and unconsciousness. Ethylene oxide can cause a wide variety of harmful health effects in exposed persons. Exposures to ethylene oxide are addressed in specific OSHA standards for general industry, maritime, and construction. NIOSH recognizes, therefore, that the continued use of ETO as a gaseous sterilant is high … Other Effects Ethylene Oxide may cause a skin allergy. Safety Information Ethylene Oxide Exposure. Exposure to ethylene oxide may cause headache, nausea, vomiting, diarrhea, breathing difficulty, drowsiness, weakness, exhaustion, eye and skin burns, frostbite, and reproductive effects. The Ethylene Oxide Panel supports policies based on the best available science and research on health, safety and environmental issues arising from the production, use, storage, transportation and disposal of ethylene oxide. 1.9 . Earth-ground and bond all lines and equipment associated with the system. Ethylene Oxide may damage the testes (male reproductive glands). EtO is both flammable and highly reactive. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. Ethylene oxide is a flammable gas with a somewhat sweet odor. Flammable Properties: EXTREMELY FLAMMABLE GAS. Ethylene oxide. Journal of Hazardous Materials 2005 , 118 (1-3) , 19-34. Ethylene Oxide may damage the developing fetus. If allergy Unfortunately, EtO possesses several physical and health hazards that merit special attention. * Skin contact with liquid Ethylene can cause frostbite. Ethylene oxide is a colorless and flammable gas with a faintly sweet odor. (1959)]. As a part of the chemical industry’s responsible management of its products, the Ethylene Oxide Panel Ethylene Oxide Safety Task Group (STG), a group comprised of producers and industrial users, developed the Ethylene Oxide Product Stewardship Manual – 3rd edition. Immediately Dangerous to Life or Health Concentrations (IDLH) CAS number: 75–21–8. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. OLYMPIC SIZE. History of Ethylene Oxide . Protecting the health and safety of the public is a top priority for the producers and users of ethylene oxide and our industry. In general, with higher levels of exposure to the chemical, more severe effects will occur. Multiple studies have shown that EO increases the risk of several types of cancer. Ethylene oxide (EtO) is produced in large volumes and is primarily used as an intermediate in the production of several industrial chemicals, the most notable of which is ethylene glycol. Ethylene oxide is expected to volatilize from dry soil surfaces (SRC) based upon a vapor pressure of 1.31X10+3 mm Hg (4). Store below 130ºF Use only stainless steel or nickel. It is a cyclic ether and the simplest epoxide: a three-membered ring consisting of one oxygen atom and two carbon atoms. Ethylene oxide is produced in large volumes and is used to make other chemicals, especially ethylene glycol, a chemical used to make antifreeze and polyester. Eng. Unfortunately, EtO possesses several physical and health hazards that merit special attention. Ethylene oxide monitoring data from July through October 2019 show little change over the previous nine months. Occupational Safety & Health Administration, Occupational Safety and Health Administration, Ethylene Oxide (EtO): Evidence of Carcinogenicity, Special Occupational Hazard Review With Control Recommendations: Use of Ethylene Oxide as a Sterilant in Medical Facilities, International Agency for Research on Cancer (IARC) Monographs on the Evaluation of Carcinogenic Risks for Humans: Ethylene Oxide, International Chemical Safety Cards (ICSC), Severe Storm and Flood Recovery Assistance. EtO is both flammable and highly reactive. It is also used as a fumigant in certain agricultural products and as a sterilant for medical equipment and supplies. All electrical equipment should be non-sparking or explosion proof. OLYMPIC SIZE. Eye contact may result in conjunctivitis (red, inflamed eyes) and erosion of the cornea. Drying ethylene oxide with magnesium perchlorate resulted in an explosion, [NSC Newsletter, Chem. Ethylene oxide may severely irritate or burn mucous membranes and moist skin. At very low Ethylene oxide (EO) is an environmental pollutant and is toxic to humans. M aterial Safety Data Sheet Issue Date: Aug. 01, 2013 ETHYLENE OXIDE Supercedes: Sep. 01, 2011 Page 2 of 12 GHS Category table for reference: Study/hazard statement Category 1 Category 2 Category 3 Category 4 Category 5 Ethylene oxide is generally synthesized by chlorohydrine process and direct oxidation of ethylene with air, catalyzed by silver(Ag). Ethylene oxide is isomeric with acetaldehyde and with vinyl alcohol. The EPA classified the chemical as a human carcinogen in 2016. Chronic exposure has been associated with the occurrence of cancer, reproductive effects, mutagenic changes, neurotoxicity, and sensitization. Note: ADAF -- EPA has concluded that ethylene oxide is carcinogenic by a mutagenic mode of action. The EPA classified the chemical as a human carcinogen in 2016. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Emergency Life-Support Procedures: Acute exposure to ethylene oxide may require decontamination and life support for the victims. 1.9 . Recommended: Chemical intermediate for production of Provides assistance and information about the management of occupational exposures to ethylene oxide. ETHYLENE OXIDE IN THE HUMAN BODY. Ethylene Oxide SAFETY DATA SHEET Effective Date: 10-1-2013 Revision: C ARC Language: EN Page 1 of 17 1. Explosive decomposition of ethylene oxide at elevated condition: effect of ignition energy, nitrogen dilution, and turbulence. It dissolves easily in water, alcohol, and most organic solvents. May 1994. News 20:1318(1942)]. GHS product identifier. Ethylene oxide (EO) is an environmental pollutant and is toxic to humans. Any potential association between ethylene oxide and cancer is linked only to chronic exposure. Avoid breathing gas. ONE. Ethylene oxide stored in the liquid state can be maintained free of explosion hazard in the gaseous phase by the introduction of nitrogen at sufficient pressure. Lists ethylene oxide as a Hazardous Air Pollutant (HAP) under the National Emissions Standard Hazardous Air Pollutants section of its Clean Air Act. If allergy Other Effects Ethylene Oxide may cause a skin allergy. Safety Information. Application Ethylene oxide can be used as a precursor to synthesize: ... Safety & Documentation. Multiple studies have shown that EO increases the risk of several types of cancer. ONE. Wear protective clothing. • Acute inhalation exposure of workers to high levels of ethylene oxide has resulted in nausea, vomiting, neurological disorders, bronchitis, pulmonary edema, and emphysema. There is minimal cancer risk for the general population because most people are not exposed to significant quantities of ethylene oxide. Ethylene Oxide. Recommended use and restrictions on use. 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